Series of 5'-Nucleotides

Nucleotides are the basic structural units of RNA and DNA. A nucleotide is composed of a nucleic acid base (nitrogenous base) and a five-carbon sugar (either ribose or 2'-deoxyribose), and one to three phosphate groups. Additionally, nucleotides play central roles in the genetics, growth and development of organism.

The resent researches from both home and broad showed that exogenous nucleotides can greatly affect the growth of gastrointestinal tract of animals and the function of immune system, liver and neuron etc. Only nucleotides supplements can ensure the normal metabolism of organism in special conditions, so nucleotides which are regarded as a kind of special additives and intermediate, which have been widely applied in the fields of food, drug and feed.

1. Drug Intermediates
 

Degradation products of RNA (Nucleotides, nucleosides and nucleic acid bases) are all medicines with a wide application, and their derivatives have more remarkable application in the fields of antivirus and anti tumors. It has been widely applied in the treatment of hepatitis, gastritis, coronary heart disease, rheumatoid arthritis, leukocytopenia, cerebral concussion, angiocardiopathy etc.
 

2. Food Additives
 

Milk powder added with nucleotides not only can improve the development of gastrointestinal tract of infants, but also improve the immunological function of intestinal cells so that build up the resistance to bacterial infection. The addition of nucleotides into functional foods would help people delay aging, extend life and improve immunity etc. Additionally, there has been a wide application of flavor nucleotides in food seasoning.
 

3. Feed Additives
 

Nucleotide is a kind of non-toxic and harmless feed additive, improving animal's immune, gastrointestinal function and fat metabolism. Such as, nucleotides can increase the feed rate of pig, improve laying rate of chicken, promoting the growth and reproduction of fishes and aquatic animals.

Series of Fructose-1,6-diphosphate

FDP is an important intracellular intermediate of metabolism that controls the activities of some key enzymes in glyco-metabolism, and repairs and improves cell metabolism at the molecular level. With effective whole-cell catalysis, bio-separation, and crystallization techniques, we obtain high-quality FDP products.

Application

1. Used as an intermediate for producing drugs in FDP salts form.

2. Used in food additives and healthy foods, replenishing the trace elements those are necessary substances for normal growth.

3. Used in feed additives for promoting animals' growth and keeping them healthy.

4. Used in clinical treatment, or adjunctive treatment, of osteoporosis and male sexual dysfunction.

α-Amylase Inhibitor, wheat origin

α-Amylase Inhibitor can inhibit the activity of amylase, which is secreted from the pancreas, in the intestine and can block/deter its digestive ability for starch, whose main component is carbohydrate. Thus, blood sugar reduced, and the increase in the blood sugar concentration is inhibited, which is beneficial in diabetic therapy. With an effective active chaperone, discovered by our company, the half-life ofα-Amylase Inhibitor activity is greatly prolonged.
 

Application

It is used as drugs and health food additives for weight reduction to prevent and treat of adiposity, lipomatosis, atherosclerosis, hyperlipidemia, and diabetes.

Casein Phosphopeptides, CPP

Casein Phosphopeptides, CPP is one of functional food additives, which is the digest of casein. It can enhance the solubility of minerals, like calsium, ferrum, zinc, magnesium and so on, and their absorption in the digestive tract. It also can increase bones mass, prevent tooth decay, improve the capacity of animal breeding, improve the body immunity, and induce apoptosis.
 

Application

1. Used as food additive. CPP can be used as nutrients added to food or health food products.

2. Used as pharmaceutical raw material.

3. Used in toothpaste, mouthwash tablets and oral fluid. To protect teeth, and to prevent dental caries.

4. Used to promote capacity of animal breeding.

5. Used as feed additive. CPP can be used to produce animal health feed of specific physiological stage.

Citicoline Sodium, CDPC

Citicoline Sodium, CDPC is endogenous intermediate of phosphatidylcholine synthesis, and an essential element in biological membrane construction. After injury of nerve, it involves in repair and regeneration of nerve, which can protect nerve. Citicoline Sodium also plays a vital role in transfer of nerve agents and conduction of biological electricity. It has significant clinical therapeutic effect on acute stroke nerve injury caused by surgery, disturbance of consciousness, Parkinson's syndrome, dementia, and glaucoma.

Application

The main indications of Citicoline Sodium are acute traumatic brain injury and brain consciousness after the operation. Moreover, Citicoline Sodium can treat central nervous system dysfunction and unconsciousness caused by acute injury, paralysis agitans, tinnitus and nerve deafness, and poisoning caused by sleeping pills. In recent years, Citicoline Sodium is widely used in clinical for treatment of ischemic stroke, cerebral arteriosclerosis, multi-infarct dementia, Alzheimer's disease, and children viral encephalitis.

S-Ademetionine, SAM

S-Ademetionine is a coenzyme found in all eukaryotic cells. SAM is a active form of methionine，animals, and it is an important metabolic intermediate in animals and plants. It also play a vital role in the human body as physiological active substance involved in more than 40 kinds of biochemical reactions. SAM is an essential donor of methyl group in cell. Its physiological function is transferring methyl, aminopropyl and sulfur group.

Application

S-Ademetionine is mainly used for the treatment of osteoarthritis (OA), depression, liver diseases such as viral hepatitis, cholestasis, liver damage caused by alcohol, liver cirrhosis and some other liver dysfunctions. It also can increase infertile men's sperm vitality, be used to treat migraines, alleviate the sequela of cerebral concussion symptoms, and have effect on muscle fiber pain and coronary heart disease.

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